New vaccine strategies resulting from progress in biochemistry and molecular biology include the production of

Answers

Answer 1
DNA vaccines, recombinant vector vaccines, and synthetic peptides.
Answer 2
DNA vaccines: DNA vaccination is a technique for protecting against disease by injection with genetically engineered DNA so cells directly produce an antigen, producing a protective immunological response

recombinant vector vaccines: Recombinant vector vaccines are experimental vaccines similar to DNA vaccines, but they use an attenuated virus or bacterium to introduce microbial DNA to cells of the body. 

synthetic peptides: In organic chemistry, peptide synthesis is the production of peptides, which are organic compounds in which multiple amino acids are linked via amide bonds, also known as peptide bonds.

Hope this helps :))

Related Questions

In humans, oxygen is effectively delivered to the tissues because of the presence of several allosteric modulators. name three of these modulators and explain how their presence allows oxygen to be delivered to the tissues.

Answers

Els moduladors al·lostèrics que actuen en els humans són el 2,3-Bisfosfoglicerat (2-3-BPG),el CO2 i els H+ . El 2,3-BPG s'uneix al centre del tetrà mer de l'estat T i així l'estabilitzà launió per interaccions iòniques. Els protons actuen perquè quan el pH és baix l'hemoglobinadisminueix la seva afinitat per l'oxigen (efecte Bohr). L'augment de la concentració del CO2 té el mateix efecte perquè el CO2 es combina en H2O i es dissocia en HCO3-i H+ i per aixòdisminueix l'afinitat de l'hemoglobina perquè augmenta la concentració de protons

What do holes in volcanic rock illustrate about the condition in which it was formed? Wright a short summery paragraph.

Answers

holes in the rock mean that after gasses and pressure build up in a volcano it spews hot magma (lava) as the magma cools it starts to turn hard but inside of the magma there are still gasses that haven't gotten out so when the magma hardens the gasses get stuck causing there to be holes. 

The laboratory report of a client reveals that the platelet count is 60,000/µl (60 x 10 9/l). which integumentary changes can be anticipated in this client? cyanosis petechiae varicosity ecchymosis hematoma

Answers

Having a platelet count of 60,000/mirol is below the normal count of 150,000 which is called thrombocytopenia. With this low platelet count, our skin which is part of the integumentary system will show signs of Petechiae. Petechiae are formed and seen on the skin when capillaries underneath leaks blood due to low platelet count. Petechiae is commonly found on a person suffering from Dengue Hemorrhagic fever Disease where platelet count decreases.

How do industrial melanism, insecticide resistance, and antibiotic resistance all support the idea of evolution and natural selection?

Answers

Industrial melanism is the resultant effect of industrial pollution on arthropods. The individuals that had a darker pigmentation were more fit to the new environment, more polluted that caused darkened buildings and trees, and were thus favoured by natural selection to survive.
Insecticide resistance and antibiotic resistance is also a manifestation of the emergence of new groups of organisms that are resistant to a specific attack out of an existing population, and are therefore favoured by selection to survive over the others.

When two average-height parents give birth to a child exhibiting achondroplasia, it is most likely due to a new mutation. this is because __________?

Answers

The question already suggests the answer: if the child has a genetic disease that both parents don't, there are only two possibilities: 

- the gene is recessive and both of the parents are carriers, but since they only have one of the genes, it doesn't manifest for them

- the gene is dominant - but then one of the parents  (or both) would have it too - so it must be a new mutation

answer: it's caused by a dominant gene

Chemical reaction equations, such as the one for photosynthesis, show the reactants and products of a reaction. How does this simplification misrepresent what takes place during the process of photosynthesis?
It does not show where in a cell photosynthesis occurs.
It does not show how long photosynthesis takes to happen.
It does not show that photosynthesis consists of many separate reactions.
It does not show the number of molecules required to produce glucose.

Answers

I would say the third option is the correct one. Although another simplification that the photosynthesis equation leaves out is the requirement of light energy needed to make glucose.

The right answer is It does not show that photosynthesis consists of many separate reactions.

It takes six molecules of carbon dioxide and six molecules of water to synthesize a molecule of glucose, releasing six molecules of oxygen, thanks to the light energy.

6 CO2 + 6 H2O + light energy ==> C6H12O6 (glucose) + 6 O2


But this balance is in fact broken down into two successive stages:

Light phase or photochemical phase:

12 H2O + light ==> 6 O2 + chemical energy (24 H).

The Calvin cycle (dark phase):

6 CO2 + chemical energy (24 H) ==> C6H12O6 + 6 H2O.

A scientist is comparing the outer layer of an onion cell to the outer layer of a human skin cell. What is unique about the outer layer of the onion cell compared to the skin cell?
It contains proteins.
It contains cellulose.
It contains carbohydrates.
It is selectively permeable.

Answers

The outer layer of the onion cell, which is a plant cell, contains cellulose, however, the human skin cell (which is an animal cell) does not contain cellulose in it. The plant cells have a rigid cell wall present around the cell membrane, which protects the cell from the outer environment and keeps it rigid. This cell wall of the plant cells is composed of the cellulose. The animal cells have no cell wall present around them, and thus, contain no cellulose.

Hence, the correct answer is 'it contains cellulose'.

The unique characteristic of the outer layer of the onion cell compared to the skin cell is that it contains cellulose.

What is cellulose?

Cellulose is a complex carbohydrate that forms the cell wall of plant cells, providing rigidity and structural support. In contrast, the outer layer of a human skin cell does not contain cellulose but is composed of keratin, a protein that gives skin its strength and durability.

While proteins, carbohydrates, and selective permeability are all important components of cellular membranes, the presence of cellulose specifically distinguishes the outer layer of the onion cell. Cellulose is a major component of plant cell walls and is responsible for their characteristic shape and structure. It provides a protective barrier and contributes to the overall integrity of the cell.

Learn more about cellulose, here:

https://brainly.com/question/13111289

#SPJ5

Individual water molecules are held to one another by relatively weak ________ bonds.

Answers

The weak bonds are called hydrogen bonds and they are used to connect the hydrogen atom to oxygen atom in order to share electrons. 

Individual water molecules are held together by relatively weak hydrogen bonds, which are stronger than other dipole-dipole forces but weaker than covalent or ionic bonds. These bonds contribute to the unique properties of water, extending its liquid state at room temperature and raising its boiling point.

Individual water molecules are held to one another by relatively weak hydrogen bonds. Hydrogen bonds occur when the negative region of one water molecule is attracted to the positive region of another molecule. Even though hydrogen bonds are stronger than other dipole-dipole forces, they are still much weaker than covalent and ionic bonds that hold the atoms within an individual molecule together. It's the collective strength of these hydrogen bonds that helps water remain liquid at room temperature, unlike other similar molecular weight substances like methane or carbon dioxide, which are gases under the same conditions.

In liquid water, there are enormous numbers of hydrogen bonds which collectively endow water with unique properties. For instance, these intermolecular interactions allow water to have a higher boiling point. The hydrogen bonds are indicated with a dotted line in scientific illustrations to reflect their relative weakness compared to the solid lines used for stronger covalent bonds.

Which organ in the lymphatic system does the breakdown of damaged red blood cells take place?

Answers

i believe the answer is liver


Answer: Spleen

Explanation:

The spleen is the organ in the lymphatic system which does the breakdwon of damaged red blood cells. It works as a blood filter and it can be found in the abdominal area.

It has two types of tissues: the red pulp tissue and the white pulp tissue. The red pulp tissue is the one who checks the levels of red blood cells storaged in our body and gets rid of the bad, preventing any risk of getting an infection.

If the gfr is too low, needed substances may pass so quickly through the renal tubules that they are not absorbed and instead are lost in urine.
a. True
b. False

Answers

The statement above is FALSE.
Glomerular filtration is the process by which the kidneys filter the blood by removing excess wastes and fluid. Glomerular filteration rate [GFR] is a measure of how well the blood is filtereed by the kidney. If the value of a GFR test is too low that indicates that the kidney is not working well.  

The tharsis bulge on mars is most likely the result of

Answers

The Tharsis bulge is probably a plume of molten mantle material that rose to Mars' surface and formed the said bulge, a rounded projection. It is also the biggest bulge with solid surfaces among all the planets known.

Identify the incorrect pair. identify the incorrect pair. synarthrosis; immovable joint amphiarthrosis; slightly movable joint chondrosis; freely moving joint gomphosis; articulation between tooth and bone they are all correct; there is no incorrect pair.

Answers

there is no incorrect pair

Minnesota department of natural resaws says has introduced regulations that require the use of approved firewood in State parks state florists and wildlife management area is there a specific approval firewood for each area which can’t be used in other protected areas what is the most likely reason for these restrictions

Answers

where are the answers to this question

Answer:

B:     To avoid the introduction or spread of insects or disease that damage native trees.

The examination of urine to determine the presence of abnormal elements is known as .

Answers

Answer:  "urinalysis" .
_________________________________

20 POINTS FOR FIRST PART AND 20 POINTS FOR THE SECOND PART
Identify the first step of the Calvin cycle and DESCRIBE what happens?

Answers

The Calvin cycle (also known as the Calvin–Benson cycle) is the set of chemical reactions that take place in chloroplasts during photosynthesis. The cycle is light-independent because it takes place after the energy has been captured from sunlight.

Final answer:

The initial step of the Calvin cycle is carbon fixation, where CO₂ is attached to RuBP to form a six-carbon compound that splits into two molecules of 3-PGA, catalyzed by the enzyme rubisco, setting the stage for the subsequent sugar production using ATP and NADPH.

Explanation:

The first step of the Calvin cycle is known as carbon fixation. During this phase, CO₂ from the atmosphere is attached to a five-carbon molecule called ribulose-1,5-bisphosphate (RuBP). This reaction is catalyzed by the enzyme ribulose-1,5-bisphosphate carboxylase/oxygenase, commonly known as rubisco. The result is a six-carbon compound that immediately splits into two three-carbon molecules of 3-phosphoglycerate (3-PGA). This is how CO₂ is 'fixed' from its inorganic form into an organic molecule, which can then be further transformed through the Calvin cycle with the help of energy carriers ATP and NADPH generated during the light reactions of photosynthesis. These energy carriers provide the necessary energy to eventually transform the 3-PGA molecules into glucose.

For the d3s1358 str locus, which allele arrangement (genotype) was suspect a?

Answers

the answer is: 14,14

Ribosomes assemble _____ to make proteins.

A) DNA

B)amino acids

C) nucleic acids

D) RNA

Answers

The right option is; B)amino acids

Ribosomes assemble amino acids to make proteins.  

Ribosomes are cell organelles found within all living cells. Within a cell, ribosome may be bound to the endoplasmic reticulum, or it may be suspended in the cytosol. Ribosomes functions as the site of biological protein synthesis. They are responsible for assembling amino acids in the order specified by messenger RNA (mRNA) molecules. Ribosomes contain two parts; (i) the small ribosomal subunits (that read the RNA), and (ii) the large subunits, (that link amino acids to create a polypeptide chain).


Ribosomes assemble RNA to make proteins. therefore option D is correct.

Ribosomes are responsible for the assembly of amino acids into proteins. This process, called protein synthesis or translation, occurs within the ribosomes in the cytoplasm of the cell.

During protein synthesis, the genetic information stored in DNA is first transcribed into RNA molecules, specifically messenger RNA (mRNA). The mRNA carries the instructions for building a specific protein from the DNA in the nucleus to the ribosomes in the cytoplasm.

Once the mRNA reaches the ribosomes, it serves as a template for protein synthesis. Transfer RNA (tRNA) molecules, which are specialized RNA molecules, bring the corresponding amino acids to the ribosome.

The sequence of nucleotides in the mRNA determines the sequence of amino acids to be joined together.

Know more about Ribosomes:

https://brainly.com/question/9333250

#SPJ6

All animals are eukaryotes. In a sentence or two, explain what this means.

Answers

A eukaryote is any organism whose cells have a cell nucleus and other organelles enclosed within membranes. Eukaryotes belong to the domain Eukaryota or Eukarya, and can be single-celled or multi-cellular.

Answer:

All animals are eukaryotes means they all have a well-defined nucleus and other organelles.

Explanation:

Eukaryotic organisms mean true nucleus. The organism has a nucleus are eukaryotes. certain exclusive characteristics:

They contain a nucleus. They have other organelles such as mitochondria, endoplasmic reticulum, Golgi body, etc.

All animals have a well-defined nucleus and other organelles.

Hence from the above discussion, we can say that All animals are eukaryotes means they all have a well-defined nucleus and other organelles.

For more you can refer to the link:  

https://brainly.com/question/21196976?referrer=searchResults

_____ is considered a pioneer in the area of suicide study.

Answers

edwin schneidman is considered a pioneer in the area of suicide study

Which of the following energy sources is expected to have the least growth in the next 20 years?
a. hydroelectricity
b. coal
c. natural gas
d. nonhydro renewables

Answers

A hydroelectricity
Renewable resource

Rolling over, crawling, and walking are all stages of which naturalist process?

Answers

The naturalist process involved in rolling over, crawling and walking would probably be part of the maturation process of mammals like man when they are infants and involve a progression in that order in learning how to stand up and walk upright eventually and in man it usually takes about one year for the walking to take place.

Which organisms are both secondary and tertiary consumers in this food web?

-Chemosynthetic bacteria and amphipods
-Zooplankton and mussels
-Ratfish and octopuses
-Galatheid crabs and zoarcid fish

Which of the following is most likely to cause the greatest disruption to an ecosystem? 
Emptying an aquarium containing non-native species into a local waterway
Cutting down a small cedar tree to make holiday decorations
Cleaning the windshield of a car with an alcohol-based glass cleaner
Mowing the lawn in a city park

During ecological succession, how does the growth of young hardwoods affect the organisms living in an ecosystem?

Grasses and low shrubs are unable to obtain the amount of light they need to survive, so there are small numbers of them.
The trees provide shelter and food for a variety of mammals, insects, and birds.
In autumn, falling leaves provide a source of energy for decomposers such as fungi.
All of the above


Answers

I believe it’s rat fish and octopus but I’m not completely sure

The organisms that are both secondary and tertiary consumers in this food web, Ratfish, and octopuses. This is because if Galatheid crabs and Zoarcid fish are removed, they become secondary consumers, but now they are tertiary consumers.

What do you mean by Tertiary consumers?

Tertiary consumers may be defined as a carnivore at the topmost rank in a food chain that forages on other carnivores.

The statement that most likely causes the greatest disruption to an ecosystem is, cutting down a small cedar tree to make holiday decorations.

During ecological succession, the growth of young hardwoods affects the organisms living in an ecosystem by all of the statements given above.

Therefore, each of the above questions may be described briefly.

To learn more about Ecological succession, refer to the link:

https://brainly.com/question/15557010

#SPJ2

The cell theory was constructed by _____. Robert Hook Schleiden and Schwann Carolus Linnaeus

Answers

the cell theory was constructed by schleiden and schwann.

Answer:

Schleiden and Schwann

Explanation:

The cell theory is the now universally believed theory that all living being are formed by cells, and the first cell theory was proposed by Theodor Shchwann and Mathias Jakob Schleiden, back in 1830, the first cell was ever observed in a microscope by Robert Hook in the 16th century but it wouldn´t be untill 2 centuries later that the cell theory started to take form.

An example in which a species is no longer found anywhere on earth is

Answers

 It is called extinction

Compare two ways that the binding of a signal molecule to a receptor protein causes a change in the activity of the receiving cell

Answers

Cell signalling is a process by which cells communicate with each other and transfer messages. When a signal molecule binds to a receptor protein, changes occur in the receptor proteins. Two changes are listed below:
1. The receptor protein undergoes conformational changes and acts as an enzyme.
2. The receptor protein that makes a second messenger molecule that leads the reaction further to other cells or molecules.

A transient condition of low hemoglobin in the blood associated with early stages of strenuous athletic training is

Answers

The transient condition that is being described above is sports anemia. This occurs when an individual is into aerobic exercise that will likely cause the individual to have his or her red blood cells to be diluted in which happens because of the plasma volume of the individual has been expanded.

If red flowering snapdragons are crossed with white flowering snapdragons, what would be the expected phenotype of the offspring

Answers

The phenotype of the offspring would be: pink.

The offspring(F1 generation) have a different phenotype than the true-breeding parents( red and white) because this is this is an example of incomplete dominance. The F1 generation is a result of a blend between the phenotypes of its parents.


Answer:

pink

Explanation:

"describe how prolonged immobilization results in muscle injury"

Answers

Rhabdomyolysis constitutes a common cause of acute renal failure and presents paramount interest. A large variety of causes with different pathogenetic mechanisms can involve skeletal muscles resulting in rhabdomyolysis with or without acute renal failure. Crush syndrome, one of the most common causes of rhabdomyolysis presents increased clinical interest, particularly in areas often involved by earthquakes, such as Greece and Turkey. Drug abusers are another sensitive group of young patients prone to rhabdomyolysis, which attracts the clinical interest of a variety of medical specialties. We herein review the evidence extracted from updated literature concerning the data related to pathogenetic mechanisms and pathophysiology as well as the management of this interesting syndrome. Keywords: Rhabdomyolysis, acute renal failure, myoglobin, crush syndrome The first case of the crush syndrome, which constitutes one of the main causes of rhabdomyolysis, was reported in Sicily in 1908, after an earthquake1,2. In 1930, in the Baltic area, an epidemic of myoglobinuria was observed due to consumption of contaminated fish. Interest in rhabdomyolysis and crash syndrome was stimulated during the World War II particularly after the bombing in London, where the victims developed acute renal failure and myoglobinuria1. Rhabdomyolysis is a rupture (lysis) of skeletal muscles due to drugs, toxins, inherited disorders, infections, trauma and compression3. Lysis of muscle cells releases toxic intracellular components in the systemic circulation which leads to electrolyte disturbances, hypovolemia, metabolic acidocis, coagulation defects and acute renal failure due to myoglobin4. The skeletal muscle consists of cylindrical myofibrils, which contain variant structural and contraction proteins. Actin and myosin, arranged in thin and thick filaments respectively, form the repeated functional units of contraction, the sarcomeres5. The sarcoplasmic reticulum constitutes an important cellular calcium storage. It is structurally connected to the t-tubules, that are formed by invaginations of the muscle cell plasma membrane, the sarcelemma, around every fibril (Figure 1). After the sarcelemma depolarization, the stimulation arrives, through the t-tubules junctions, at the sarcoplasmic reticulum, inducing the calcium ions release and triggering muscle contraction6.

Prolonged immobilization causes muscle atrophy, which leads to muscle weakening and reduced function due to the muscles not receiving regular stimulation. Improper immobilization of fractures can cause misalignment during healing, further injuring muscles. Exercise and rest are crucial for preventing and recovering from muscle injuries, while improper technique can lead to overuse injuries.

Prolonged immobilization can have detrimental effects on muscle tissue, leading to muscle atrophy and injury. When muscles are not subjected to regular activity or strain, such as in cases where individuals experience extended bed rest, spaceflight, or being immobilized due to injury, they begin to weaken and decrease in size.

The muscle fibers become smaller, resulting in overall muscle weakening, which, in turn, diminishes strength and function. This process occurs because the muscles are deprived of the regular stimulation needed for maintaining muscle mass and protein content.

Additionally, immobilization can lead to the damage of syndesmotic joints and the associated muscles. If a fracture is not properly immobilized, the muscles that are still trying to contract can cause misalignment during the healing process, exacerbating the injury and leading to prolonged recovery times.

Furthermore, when muscles have undergone significant damage, their capacity to produce power is compromised due to the loss in muscle fiber quantity and quality. Regular exercise and stretching are essential to prevent muscle injury and to encourage recovery and strength-building following an injury.

However, it is critical to balance exercise with adequate rest, as overuse injuries can occur from activities such as resistance training without proper rest and recovery time. These injuries may include damage to muscle fibers, tendons, or bones, and they highlight the need for careful alignment and technique during exercises to prevent further harm to the muscles.

Organisms that live in the alpine and taiga biomes have developed unique adaptations that aid in their survival. The Douglas-fir is a conifer tree that grows in the taiga biome. It has an average height of about 70 feet, and its wood is an important source of lumber. Photo by Anne Burgess How has the Douglas-fir adapted to enable its survival in the taiga biome? a. low growing b. perennial c. waxy needles d. survive on limited nutrients

Answers

the correct answer is C

Answer:

C. Waxy needles

Explanation:

Taiga is one of the coldest biomes of the world. It is dominated by coniferous woody trees. It recieves very little or no rainfall during winter months. Trees of Douglas fir exhibit waxy needles to prevent the loss of water through transpiration in the scarcity of water.

When assessing abdominal pain in a college-age woman, one must include'?

Answers

The first day of last menstrual cycle.

Answer:

When evaluating abdominal pain in a university woman, one can infer that it is an endometriosis

Explanation:

Endometriosis is defined as a very common gynecological disorder in women of childbearing, benign age, and depends on estrogen. Although its highest frequency is in women between 25 and 45 years old, it can also occur at the time of the first menstruation. Its main symptoms are pelvic pain, coupled with menstruation, infertility, etc. When there is a compromise in the gastrointestinal system, abdominal pain, pain in the rectum, nausea, vomiting, etc. can be felt.

Other Questions
Assume that a randomly selected subject is given a bone density test. those test scores are normally distributed with a mean of 0 and a standard deviation of 1. find the probability that a given score is less than 1.66 and draw a sketch of the region. McKenzie bought 1.2 pounds of coffe for $11.82. What was the cost per pound? 5. What does Civic-Mindedness primarily encourage people to do?A. to speak their minds about issues honestlyB. to treat other citizens with respectC. to pay attention to government affairsD. to study the history of the United States6. Which are true of majorities and pluralities? Select all that apply.A. A majority is a position held by more thank half of a groupB. A plurality is a position held by more thank half of a groupC. A majority is a position held by less than half of the group but still is the most popular decisionD. A plurality is held by less than half of the group but still is the most popular decisiondon't just say something about "were is your answers" or anything like that just answer the question since you will be getting 50+ points George spent 70 % of his saving to buy a camera. The camera cost $574 . How much did he originally have in savings? An example of physical capital would be: a truck a worker buys for personal use like hunting, going to work, or going to the beach. a worker who physically learns to work on a truck his company buys. a truck a company purchases for work. a truck a company purchases for work, a worker who physically learns to work on a truck his company buys, or a truck a worker buys for personal use like hunting, going to work, or going to the beach. Which excerpt from The War of the Worlds uses a vivid visual description for aesthetic impact? A)"I saw the shopman struggling still on the edge of the pit." B)"I found myself alone, and saw the people on the other side of the pit running off, Stent among them." C)"A lank tentacular appendage gripped the edge of the cylinder, another swayed in the air." D)"Even at this first encounter, this first glimpse, I was overcome with disgust and dread." The eradication of african river blindness (onchocerciasis) illustrates the connection between: The expression 0.09x+(x30) models the final price of a bicycle with an instant rebate in a state that charges a sales tax. The tax is on the original price. Which expression represents the amount of tax that is paid on the bicycle? A) 1.09x B) 0.09x C) 0.09x - 30 D) x - 30 what is the difference between a reactant and a product? What do you rely on when surrounded by difficulties? Check any that apply.information I have gotten from own experienceadvice I have received from othersmy gut instinctsmy logic and planning skills my strength and enduranceother peoples support How to remove sodium chloride from silica? True or false more than 3000 Americans die each year from choking Richard estimates that he can apply fertilizer to 4,485 square feet of grass in 3/4 of an hour. How many square feet of grass can Richard fertilize per hour? Prove the quotient of any two rational numbers is a rational number If a triangle is an isosceles triangle, then it has two sides of equal length. If a triangle has two sides of equal length, then it has two angles of equal measureConclusion:If a triangle is an isosceles triangle, then it has two angles of equal measure.The argument is not valid because the conclusion does not follow from the premises.The argument is valid by the law of syllogism.The argument is not valid because the premises are not true.The argument is valid by the law of detachment. Please Help!Which is true about the domain and range of a function in the form f(x) = m, where m is a real number greater than 0?The only value that must be in both the domain and range is 0.The only values that must be in both the domain and range are 0 and 1.There are no values that are in the domain and the range.There is an infinite number of values that are in both the domain and range. A data firm records a large amount of data. historically, 1.0% of the pages of data recorded by the firm contain errors. if 200 pages of data are randomly selected?a. what is the probability that six or more pages contain errors?b. what is the probability that more than 10 pages contain errors?c. what is the probability that none of the pages contain errors?d. what is the probability that fewer than five pages contain errors? Biomes that are found near the equator or near mountains ranges and have high relative humidity and lots of rain are called A) deserts. B) rain forests. C) temperate forests. D) deciduous forests. Which of the following items are true of early nuclear science?(Multiple choice) The first nucleus split was uranium-235.The first nuclear reactions were done in the 1880s.Albert Einstein himself caused the first nuclear reaction.some mass of the nucleus was lost in the first nuclear reaction. Why do companies choose to outsource work?to increase profitsto improve productsto cut transportation coststo develop local resources Steam Workshop Downloader