Many drugs can be applied to the skin without entering the blood. how is this fact explained?

Answers

Answer 1
While the outer layer of the skin acts a physical barrier, the skin is porous. It's the same reason sweat appears on our skin when we're hot. 
Answer 2

*A drug administered by the cutaneous route can have one of these three actions:

Local action, superficial: ex. local anesthetic ...

Deep action: ex. anti-inflammatory action ...

Systemic or general action: ex. anti-anginal action

*The skin is a very effective barrier, which limits the number of drugs that can enter the system.

*The factor influencing the penetration of the drugs are:

- Nature and physicochemical properties of P.A: Molecular weight, hydrophilicity, lipophilicity, stability ...

- Formulation of the drug: Excipients lipophilic, hydrophilic, amphiphilic, an absorption promoter

- Nature and condition of the skin, Location, age, thickness (1 to 8 mm ...), vascularization...

*To not penetrate the skin, a drug should have to be of high molecular mass (to be unable to penetrate through the skin tissue), hydrophilic (since the skin is of a lipophilic nature).

*For example, solar creams should not enter the system so the excipients used are hydrophilic in nature.


Related Questions

This is what an oak tree does at the theater when the movie ends

Answers

The answer could be "leaves". The plural of leaf (the principle photosynthetic organ of a plant) is leaves, which coincides with the third person of the singular of the verb to leave in the present tense - (it/he/she) leaves.

One of the bladder's main functions is to __________. A. absorb water in the body B. filter the blood C. connect the kidney to the urethra D. store urine before elimination

Answers

The correct answer is D. Store urine before elimination.

Bladder is termed as a hollow muscular organ which is found in some animals and human which stores and collects urine from the kidney before it is being disposed by way of urination.

It is via the ureters is how urine enters the bladder and its exit is urethra.

A normal human can hold a maximum of 500mL before an urge of emptying occurs.

Answer:

D. store urine before elimination

Explanation:

One of the bladder's main functions is to __________.

Markets distribute goods and services based on

Answers

Price.
Best of luck! :)

fill in the name of the processes such as freezing that are represented

Answers

a) melting (the passage from a crystal conformity to a liquid conformity because of more energy associated to its molecules)
b) boiling (the passage of a liquid to gas, usually by quick transition because of an increase of temperature)
c) freezing (when a liquid becomes solid by decrease of temperature, becoming a crystallised structure) 
d) condensation (the passage from gas to liquid, it requires cooling the gas making the particles closer forming a more solid fluid then a gas - a liquid)
Final answer:

These are names of processes linked to the changes in physical states and properties of matter. They include an isentropic process with no change in entropy, irreversible processes which cannot return the system or surroundings to an initial state, isothermal processes that operate at constant temperatures, isobaric and isochoric processes that maintain constant pressure and volume respectively.

Explanation:

The name of the processes such as freezing can be related to the ones annotated in the representation below.

Isentropic: This is a process that proceeds without any change in entropy. It's an ideal process that assumes perfect insulation, hence no exchange of heat with the surroundings.Irreversibility or Irreversible Process: These are processes that cannot return the system or the surroundings to its initial state. Heat transfer, free expansion, mixing of gases, and chemical reactions are examples.Isothermal Expansion or Isothermal Process: These are transformations that take place at a constant temperature. Gas expansion with heat addition is an example.Isobaric process: This is a thermodynamic process whereby the pressure remains constant.Isochoric process: A process during which the volume remains constant.

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Identify 2 ways organisms reproduce

Answers

Organisms reproduce by asexual reproduction (the splitting of cells) or sexual reproduction(the birth of living young(eggs, living young, etc.)). Hope this helped.


A large hole that opens in the ground as a result of overpumping groundwater is a _____.

subsidence

sinkhole

intrusion

cavern

Answers

It is b. A sinkhole. Cause the hole will open and everything fall in it
sinkhole. ihope this helps dude 
:)

the levels of carbon dioxide are at the highest that they've ever been in the history of Earth.

True or False

Answers

true
that is correct
really you dont know about global warming and the answer is yes

label and illustrate an autotroph and a heterotroph organism. i used all my points for this pretty please answer. you will save 10%of my grade

Answers

Autotroph = grass, tree, or any regular plant really (so draw one of those and label it autotroph
Heterotroph = dog, cat, bird, fish

Heterotrophs(dog, deer, tiger, etc.) get their food from autotrophs(plants).

What are autotrophs?Autotrophs animals are those that make their own food.Example: all green plants.What are heterotrophs?Heterotrophs animals are those that do not make their own food but are either directly or indirectly depend on plants for their food.Example: deer(primary consumer), fox(secondary consumer), tiger(tertiary consumer).

Hence, heterotrophs depend on autotrophs is shown in the given diagram.

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which is an ion found in a glass of water

Answers

B. H+ That’s the correct answer for apex

It's.

_

OH

This is the anwser on apex

A neutral atom of oxygen has 8 protons and ______ electrons. (Enter a whole number.) Numerical Answers Expected!

Answers

Answer:

8 electrons

Explanation: there are the same amount of protons and electrons in a atom

Final answer:

A neutral atom of oxygen has 8 protons and 8 electrons.

Explanation:

A neutral atom of oxygen has 8 protons and 8 electrons. Oxygen is an element with atomic number 8, which means it has 8 protons in its nucleus. Since atoms are neutral, the number of electrons in an atom is also equal to the number of protons. Therefore, an oxygen atom has 8 electrons.

During the process of _____, two rails or sides break apart and attract new nucleotide bases to form a new and complete strand.

Answers

A bond, called the glycosidic bond, holds the base to the sugar and the 3′-5′ ("three prime-five prime") phosphodiester bond holds the individual nucleotides together. Nucleotides are joined from the 3′ carbon of the sugar in one nucleotide to the 5′ carbon of the sugar of the adjacent nucleotide. The 3′ and the 5′ ends are chemically very distinct and have different reactive properties. During DNA replication, new nucleotides are added only to the 3′ OH end of a DNA strand. This fact has important implications for replication.
During the process of replication

The ph scale ranges between___ and ___

Answers

The ph scale ranges between 0 to 14. I hope this helps love! :)
The ph scale range between zero to fourteen

What is one way that early scientific practice differed from modern scientific practice? Early hypotheses were not based on observations. Early hypotheses were not tested by experimentation. Early hypotheses were formed from scientific questions. Early hypotheses were influenced by creative thinking.

Answers

Early hypotheses were not tested by experimentation.

One way early scientific practice differed from modern scientific practice is that early hypotheses were not tested by experimentation. In earlier times, many ideas were often developed based on philosophical reasoning, deductive logic, or theoretical speculation without the rigorous experimentation and empirical testing that are central to modern scientific methods.

Over time, the emphasis has shifted to the use of controlled experiments and systematic observation to test hypotheses and validate scientific theories.

Twin boys both have a gene associated with aggressive tendencies. what is the most likely outcome to be observed in their behavior as they grow up?

Answers

It is not possible to determine the twins'  behaviors based on having this single gene  

Give two examples of environments that involve more than one sphere.
I will give brainliest.

Answers

a swamp involves the biosphere and the hydrosphere

a farm involves the biosphere and the atomosphere

Which of the following best describes homeostasis?

The maintenance of an organisms internal environment within certain limits.

The maintenance of an organisms external environment within broad limits.

Answers

the maintenance of an organisms internal environment within certain limits

Answer:

The Correct Answer is

The maintenance of an organism's internal environment within certain limits.

Explanation:

Homeostasis is the consistency and the state of balance of the system.

It further explains the ability of the physiological processes of the internal environment to maintain a relatively steady-state even though the outside world is changing continuously.

There are two types of Homeostasis; Physiological and Psychological.

which organelle of a prokaryotic cell contains genetic information? A.ribosomes B. nucleus C. nucleoid D. cell membrane

Answers

The right option is; C. nucleoid

Prokaryotic cells are simple cells that lacks a definite nucleus and some membrane bound organelles. Prokaryotic cells have a nucleoid region, which is an irregularly-shaped central region of the cell that contains the cell’s genetic information (DNA). Other organelles that can be found in prokaryotic cells include plasma membrane, cell wall, cytoplasm and ribosomes.

Nucleoid is an organelle of a prokaryotic cell that contains genetic information.

Further Explanation Living organisms are classified as either eukaryotes or prokaryotes. Eukaryotes Eukaryotes are living organisms that contain a nucleus and other membrane bound organelles. The function of the nucleus being storage of genetic materials and also controlling all cellular activities. Eukaryotes are either single celled or multicellular for organisms such as plants, animals, and fungi. Prokaryotes Prokaryotes are organisms that lack a nucleus and other membrane bound-organelles such as ribosomes, Golgi apparatus, endoplasmic reticulum, etc. Genetic information in prokaryotes is contained in a nucleoid which is a concentration of DNA that lacks an enclosing membrane. Nucleoid contains large circular DNA that has genes that are required for the survival and reproduction of the cell. Other Cellular organelles. Nucleus Nucleus is a type of cellular organelle found in eukaryotic cells whose function is to control all the cellular activities undertaken by the cell.  Additionally, the nucleus house the DNA which carries the genetic material of an organism. Mitochondrion This is one of the cell organelle inside a cell. It is referred as the powerhouse of the cell, as it is where energy to drive all cellular activities is generated through the process known as cellular respiration. Ribosomes  These are organelles where the synthesis of proteins takes place through a process known as translation. They are found in the cytoplasm, either freely suspended or attached to rough endoplasmic reticulum. Cell membrane  It is a structure that encloses the cell contents in the cytoplasm from the external environment. It’s functions is to control materials entering in and out of the cell through selective permeability.

Keywords: Prokaryotes, nucleoid, nucleus, genetic information

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Level: High school

Subject: Biology  

Topic: Classification of living organisms  

Sub-topic: Prokaryotes and eukaryotes  

__________ lenses refract light rays in toward a central point. When this lens is held close to your eye, the image is magnified and right side up.

Answers

I think the answer for this is 'convex'

Answer: Convex

Explanation:

Convex lens refracts the light rays in towards a central point. These lenses are thicker at the middle and when the light rays are passed through it then all the rays are bought close together.

If this lens is placed close to your eyes then image looks slightly magnified because it thicker at the middle.

The element nitrogen has the atomic number 7 and an atomic mass of 14. How many neutrons does an atom of nitrogen contain?

Answers

It would contain 7 neutrons. To find how many neutrons any element has, simply take the atomic mass and subtract the number of protons (atomic number) front that.
The element nitrogen has 7 neutrons.

if different individuals of a species of mouse have different alleles they will also have different A. genders B. parents C. cells D. traits

Answers

i would say D) traits 

have a wonderful rest of ur day

Answer:

The correct answer is option  D. "traits".

Explanation:

Alleles are specific forms of genes that determine the developed of certain trait in an organism. Alleles are responsible for the development of traits, for instance, the fur color of mice is determined by the expression of different alleles. Therefore, if different individuals of a species of mouse have different alleles they will also have different traits.

The events taking place in two different locations are described below: Location A: Movement of plates causes hot spots to move to a location with thinner crust Location B: Tectonic plates move away from each other under the sea In which location will active volcanoes most likely be formed and why? Location A, because the magma breaks through the thin crust Location A, because cracks between plates are filled with molten rocks which solidify Location B, because the oceanic plate and continental plate are pushed up through the crust Location B, because the thinner oceanic plate will be pushed under the continental plate

Answers

Location B, because the oceanic plate and continental plate are pushed up through the crust

Answer:

The correct answer is A

Location A, because the magma breaks through the thin crust

Explanation:

Which of the following functional groups contains only carbon, hydrogen, and oxygen? A) carboxyl group B)amino group C)sulfhydryl group

Answers

A. carboxyl group

amino - is nitrogen containing
sullf - is sulfur containing

The functional group that only contains carbon, hydrogen, and oxygen is carboxyl group. The correct option is A.

What is a functional group?

Functional groups are groups of atoms in a substance that control the complex's chemical behavior include groupings like the hydroxyl group in an alcohol.

The functional group refers to the area of a substance that interacts with another component.

An atom or group of atoms known as a functional group is in charge of a certain chemical characteristic of an organic molecule.

Functional groups are a way to categorise organic molecules. An organic compound with a functional group has a different attribute from what it would otherwise have.

The two functional groups hydroxyl (single-bonded OH) and carbonyl (double-bonded O), which are both connected to one carbon atom, are combined to form carboxyl groups.

The amino group have nitrogen along with carbon, hydrogen, and oxygen, while sulfhydryl group have sulfur in addition.

Thus, the correct option is A.

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Rocks created from compaction and cementation of sediments are called A)sedimentary
B)metamorphosis
C)igneous
D)metamorphic

Answers

The answer is A)Sedimentary.
it’s a i think. hope it helps

Why do enzymes generally only bind to one type of substrate?

Answers

They only "fit" with one type. If they don't fit right they don't do their job.

5. Based on your reading, what makes it so that you are able to literally walk on the ocean floor in the Bay of Fundy?

Answers

Based on the reading it makes me able to literally walk on the ocean floor in the Bay of Fundy is during high tide, the water levels are extremely high. But, during low tide, it is possible to walk on the ocean floor and look up at the rocks above.

sphere do you think is the most important to study and why your answer should include information about all four spheres (hydrosphere lithosphere atmosphere and biosphere)

Answers

Answer:

HYDROSPHERE

Explanation:

The lithosphere is the solid outer portion of earth. It includes the crust and a small portion of the upper mantle. The rocks present in this region are determined which are hard and undergoes deformation due to the stress that acts on it. The region has been explored and sufficient data has been acquired.

The atmosphere is defined as the gaseous envelope that surrounds the earth. The different layers of atmosphere has been constructed depending upon its height and temperature. The composition of atmosphere is also identified that are present in a definite amount. This amount can either increase or decrease due to the changes in the earth's surface.

The biosphere is the region that includes the hydrosphere, atmosphere and lithosphere where life occurs and interacts between them. Sufficient study has been made regarding this zone and were able to understand how life occurs depending upon the various factors.

The hydrosphere refers to all the water bodies on earth, including the glaciers and the ice bergs.  

The terrestrial areas have been explored easily because it is possible for a person to visit those sites but it is not possible to go at a deeper depth to study the structure and the components of the deep water bodies. Although, much of the information has been regarding this sphere, but still the deep water portion such as the deep sea trenches are yet to explore. It is not possible because at this depth, the pressure is extremely high and lift is normally difficult to exist at this pressure condition. But there are some animal and plant species that can grow and survive at this condition.

So, much more is needed to study regarding the hydrosphere.

The most important sphere to study may vary by perspective, but all four spheres, the lithosphere, hydrosphere, atmosphere, and biosphere, are interdependent, influencing Earth's climate, geography, and life.

Understanding the different spheres of Earth is crucial because they are deeply interconnected and collectively influence the planet's climate, geography, and life. The four main spheres are the hydrosphere, lithosphere, atmosphere, and biosphere. The lithosphere includes solid rock, soil, and minerals. The hydrosphere encompasses all forms of water on the planet. The atmosphere refers to the layer of gases surrounding the Earth, and the biosphere comprises all forms of life and their interactions with the other spheres.

Each sphere is important in its own right, but if we must consider which sphere is the most crucial to study, it could vary depending on the perspective and context. The hydrosphere is often emphasized due to its essential role in the water cycle and life support, interacting dynamically with the atmosphere, lithosphere, and biosphere. This interaction includes fundamental biogeochemical cycles, such as those for water, carbon, and nitrogen, which are critical for life on Earth.

However, determining which sphere is the most important is subjective and largely depends on what aspect of Earth's systems one considers most vital. The lithosphere provides the foundation for habitats and is a source of valuable resources, the atmosphere is crucial for climate and weather patterns, the hydrosphere is indispensable for all life, and the biosphere is the sum of all ecosystems. The study of any single sphere is incomplete without considering its interactions with the others.

what effect does the presence of existing soil in secondary succession have on the amount of time it takes to return to the climax community compared to primary succession

Answers

the primary succession takes a long time to be done. the secondary succesion takes 200-500 years for completion. the secondary succession occurs in an area which has been denuded recently and lately inhabited. soil is present at the beginning of the secondary succession with some organisms. thank you for this question.

What is the main purpose of aquaculture

Answers

The Purpose of Aquaculture. The rationale for the culture and management of aquatic animals and plants has remained unchanged for centuries. Fish farming has been a traditional means of producing food intended for immediate consumption at the village level.

which of the following parts of a nuclear power plant is turned on by steam
A.Control rods
B.Ractor vessel
C.Turbine
D.Generator

Answers

I think it would be C 

Answer:

Option (C)

Explanation:

A nuclear power plant is considered to be a thermal power station where the main source of heat is the nuclear reactor. Here, energy is released in the form of heat that helps in generating steam. This steam then initiates the motion of the turbines that are connected to a generator. These turbines when rotates produce electricity.

These nuclear plants are less costly and they do not emit any kind of pollution. They are very efficient to use but has certain disadvantage, that the waste materials it releases contain some amount of radioactive element in them and are difficult to dump.

Thus, the turbines in a nuclear power plant is turned on by the steam.

Hence, the correct answer is option (C).

Which statement describes a negative consequence of humans’ use of excess water?
It allows food to be produced in dry areas.
It increases runoff, which carries fertilizers.
It enables food to be produced in drought years.
It results to water not being recycled.

Answers

The statement that describes negative consequences of humans' use of excess water is choice number two in which it increases run off, which carries fertilizers. Run off means of having to drain water and if it increases, it will only result into having it to be wasted where in it is important and vital as it is important for humans as well as plants and animals.

Answer: B. It increases runoff which caries fertilizer

Explanation:

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